HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → {8-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-5-yloxy}-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole | HCID 1481100 | — |
| Reactant | (8-Mercapto-chroman-5-yloxy)-acetic acid methyl ester | HCID 11288267 | — |
| Product | {8-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-5-yloxy}-acetic Acid | HCID 22280159 | — |
Reaction Steps
The title compound was prepared in the manner analogous to Example 1F using 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole and (8-mercapto-chroman-5-yloxy)-acetic acid methyl ester. mp 131-133° C.; MS m/z 446 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964983B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-7a4a1e6f0a2841d2aebe2015dcf7b381 |
| Source note | uspto-grants-2005_11 |