HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-Bromo-5-fluorobenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | HCID 22144926 | HCID 22144926 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Bromo-5-fluorobenzofuran | HCID 22144695 | 98% |
Reaction Steps
Beginning with 3 gm (13 mMol) 2-allyl-3-bromo-4-fluorophenol, the title compound was prepared in 98% yield essentially by the procedure described in Preparation XXVII with the exception that the cyclization/dehydration step was performed using sulfuric acid in toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06967201B1 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-c71d8776648843fb9ebf87ebfc6dd851 |
| Source note | uspto-grants-2005_11 |