Sulfuryl chloride → N,N-diethylsulfamoyl chloride

HRID 1063907Notes

Reaction equation

HRID 1063907 reaction equation
Cl.[CH2:2]([NH:4][CH2:5][CH3:6])[CH3:3].[S:7](Cl)([Cl:10])(=[O:9])=[O:8]>>[CH2:2]([N:4]([CH2:5][CH3:6])[S:7]([Cl:10])(=[O:9])=[O:8])[CH3:3]

Participants

3

Reactant 2

HCID 24648Sulfuryl chlorideHCID 10197650Diethylammonium chloride

Product 1

HCID 11252267N,N-diethylsulfamoyl chloride

Procedure

A solution of diethylamine hydrochloride (1 g) in sulfuryl chloride (10 ml) was heated at 50° C. for 4 hours. The solution was allowed to cool to ambient temperature and sulfuryl cloride was evaporated in vacuo. To the residue were added ethyl acetate and water. The organic layer was washed with brine, dried over anhydrous magnesium sulfate and concentrated in vacuo to give diethylsulfamoyl chloride (720 mg) as a colorless oil.

Workup

  1. customsulfuryl cloride was evaporated in vacuo
  2. additionTo the residue were added ethyl acetate and water
  3. washThe organic layer was washed with brine
  4. dry with materialdried over anhydrous magnesium sulfate
  5. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-c9689078cce94203bc3f9664f4463d98
Source dataset
uspto-grants-2005_11
Patent number
US06967197B2

Reaction notes

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