Hydrochloric Acid → HCID 86588735, compound

Participants

Reaction Steps

To a solution of N-(2-tetrahydropyranyloxy)-2-[(S)-7-(5-(2-furyl)-2-thienyl)-4-tert-butoxycarbonyl-1,1-dioxoperhydro-1,4-thiazepin-7-yl]acetamide (160 mg) in methanol (5 ml) was added 4M hydrogen chloride in ethyl acetate (5 ml) at room temperature. After being stirred for 1 hour, the mixture was concentrated in vacuo. The resulting residue was triturated with diethyl ether to afford N-hydroxy-2-[(S)-7-(5-(2-furyl)-2-thienyl)-1,1-dioxoperhydro-1,4-thiazepin-7-yl]acetamide hydrochloride (75 mg) as a powder.

Provenance & Evidence