HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(Methylsulfonyl)methyl]piperidine → HCID 86759906, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(Methylsulfonyl)methyl]piperidine | HCID 22275213 | — |
| Reactant | HCID 23401651 | HCID 23401651 | — |
| Reactant | HCID 23401686 | HCID 23401686 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86759906 | HCID 86759906 | 28% |
Reaction Steps
4-chloro-N-(2,5-dichlorophenyl)-N-[4-[[2-(methylsulfonyl)methyl-1-piperidinyl]-1(R)-methylbutyl]benzenesulfonamide was prepared analogous to 4-chloro-N-(2,5-dichlorophenyl)-N-(3-(2-((methylsulfonyl)methyl)-1-piperidinyl)-1(R)-methylpropyl)benzenesulfonamide by reacting 4-chloro-N-[2,5-dichlorophenyl]-N-[(R)-1-methyl-4-bromobutyl]benzenesulfonamide with 2-(methylsulfonylmethyl)piperidine. Yield=28%; yellow foam: IR (neat, CH2Cl2) 1467, 1296, 1166, 1138, 1095, 622, cm−1; MS (ESI+), 581 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06967196B1 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-a50740ec1fe04d5aa239188009591bc1 |
| Source note | uspto-grants-2005_11 |