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HRID1063979

反应详情

EQUATION

反应方程式

HRID 1063979 的结构方程式

REACTANTS

反应物

3
结构：CNC
HCID674

Dimethylamine

C2H7N

结构：CCCCCS(=O)(=O)Cl
HCID237555

1-Pentanesulfonyl chloride

C5H11ClO2S

结构：CNS(=O)(=O)CCC[C@@H](C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
HCID23401749

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](CCCS(=O)(=O)NN(C)C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
HCID23401747

未命名化合物

收率 73%

PROCEDURE

实验过程

4-chloro-N-[5-chloro-2-(hydroxymethyl)phenyl]-N-[4-(dimethylaminoaminosulfonyl)-1(R)-methylbutyl]-benzenesulfonamide was prepared analogous to 4-chloro-N-[5-chloro-2-(hydroxymethyl)phenyl]-N-[4-[(methylamino)sulfonyl]-1(R)-methylbutyl]benzenesulfonamide by reacting (4R)-4-[5-chloro-2-(acetoxymethyl)phenyl][4-chlorophenyl)sulfonyl]-amino]pentylsulfonyl chloride with dimethylamine. Yield=73%; MS (ESI+), 509 (M+H)+.