HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 23401747, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1-Pentanesulfonyl chloride | HCID 237555 | — |
| Reactant | HCID 23401749 | HCID 23401749 | — |
| Product | HCID 23401747 | HCID 23401747 | 73% |
Reaction Steps
4-chloro-N-[5-chloro-2-(hydroxymethyl)phenyl]-N-[4-(dimethylaminoaminosulfonyl)-1(R)-methylbutyl]-benzenesulfonamide was prepared analogous to 4-chloro-N-[5-chloro-2-(hydroxymethyl)phenyl]-N-[4-[(methylamino)sulfonyl]-1(R)-methylbutyl]benzenesulfonamide by reacting (4R)-4-[5-chloro-2-(acetoxymethyl)phenyl][4-chlorophenyl)sulfonyl]-amino]pentylsulfonyl chloride with dimethylamine. Yield=73%; MS (ESI+), 509 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06967196B1 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-190edd642c2e48d381519e7d5bc0b149 |
| Source note | uspto-grants-2005_11 |