Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Pyridinecarboxaldehyde | HCID 13389 | — |
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69357913 | HCID 69357913 | — |
Reaction Steps
To mixture of (4-Chloro-phenyl)-acetic acid 9.78 g and pyridine-4-carbaldehyde 6.14 g was added acetic anhydride 20 mL and triethyl amine 20 mL. The reaction mixture was heated to 120° C. for 24 hours and cooled down to room temperature. Water and ethyl acetate were added. The solids formed was filtered, washed with water and ethyl acetate and dried to afford the title compound as a light yellow solid. MS (ES+): 260 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06967254B2 |
|---|
| Source dataset | uspto-grants-2005_11 |
|---|
| ORD ID | ord-b40728c1bd5b4f7da6ddb5bf40eda83e |
|---|
| Source note | uspto-grants-2005_11 |
|---|
