反应详情

温度

120 °C

To mixture of (4-Chloro-phenyl)-acetic acid 9.78 g and pyridine-4-carbaldehyde 6.14 g was added acetic anhydride 20 mL and triethyl amine 20 mL. The reaction mixture was heated to 120° C. for 24 hours and cooled down to room temperature. Water and ethyl acetate were added. The solids formed was filtered, washed with water and ethyl acetate and dried to afford the title compound as a light yellow solid. MS (ES+): 260 (M+H)+.

1. temperaturecooled down to room temperature
2. customThe solids formed
3. filtrationwas filtered
4. washwashed with water and ethyl acetate
5. customdried