HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064072Generated: October 31, 2026
Hydrazine → 4-(4-Chloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one
https://huagongshe.com/reaction/1064072
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 69356330 | HCID 69356330 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-Chloro-phenyl)-5-pyridin-4-yl-pyrazolidin-3-one | HCID 22277989 | — |
Reaction Steps
To a solution of 2-(4-Chloro-phenyl)-3-pyridin-4-yl-acrylic acid methyl ester 2.02 g in ethyl alcohol 25 mL was added hydrazine 2.37 g. The reaction was heated to 50° C. for 135 minutes. All solvent was removed after under reduced pressure to afford the title compound as light yellow solid. MS (ES+): 274 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06967254B2 |
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| Source dataset | uspto-grants-2005_11 |
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| ORD ID | ord-d7fe7a69bcd14183b4ac978d02affae1 |
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| Source note | uspto-grants-2005_11 |
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