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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064076Generated: October 31, 2026

Hydrochloric Acid → HCID 9928554, compound

https://huagongshe.com/reaction/1064076

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 69357048HCID 69357048—
SolventDiethyl EtherHCID 3283—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 9928554HCID 9928554—

Reaction Steps

To a solution of 4-[4-(4-Chloro-phenyl)-3-oxo-5-pyridin-4-yl-2,3-dihydro-pyrazol-1-yl]-piperidine-1-carboxylic acid tert-butyl ester 200 mg in flask was added HCl in ether and dioxane. After 2.25 hours, the solvent was evaporated under reduced pressure to afford the title compound as yellow oil. MS (ES+): 355 (M+H)+; (ES−): 353 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06967254B2
Source datasetuspto-grants-2005_11
ORD IDord-f3227960537d4a8588a4dfe254704bf8
Source noteuspto-grants-2005_11