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HRID1064227

反应详情

EQUATION

反应方程式

HRID 1064227 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)C#N
HCID69430

2-Oxopropiononitrile

C3H3NO

结构：Cc1c(OCc2ccccc2)cn2ncnc(Cl)c12
HCID11637630

6-Benzyloxy-4-chloro-5-methylpyrrolo[2,1-f][1,2,4]triazine

C14H12ClN3O

结构：Cc1cc2cc(O)cnc2[nH]1
HCID22273621

2-Methyl-1H-pyrrolo[2,3-b]pyridin-5-ol

C8H8N2O

PRODUCTS

生成物

1
结构：Cc1cc2cc(Oc3ncnn4cc(OCc5ccccc5)c(C)c34)cnc2[nH]1
HCID22273637

未命名化合物

PROCEDURE

实验过程

5-Hydroxy-2-methyl-7-azaindole was treated with of 6-benzyloxy-4-chloro-5-methyl-pyrrolo[2,1-f][1,2,4]triazine (see WO 0071129) by a method similar to the preparation of Example 1. 1H NMR (400 MHz, DMSO-d6) δ 8.02 (1H, br. s), 7.85 (1H, s), 7.83 (1H, s), 7.70 (1H, br. s), 7.41 (6H, m), 6.15 (1H, br. s), 5.12 (2H, s) 2.92 (3H, s), 2.42 (3H, s). m/z 386 (M+H)+, 427 (M++AcCN).