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HRID1064276

反应详情

EQUATION

反应方程式

HRID 1064276 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccccc1F
HCID2734354

(2-Fluorophenyl)boronato(2-)

C6H6BFO2

结构：Fc1ccc(-c2nncc(-c3ccc(F)c(Br)c3)n2)c(F)c1
HCID10384255

未命名化合物

PRODUCTS

生成物

1
结构：Fc1ccc(-c2nncc(-c3ccc(F)c(-c4ccccc4F)c3)n2)c(F)c1
HCID10339795

5-(2′,6-Difluoro[1,1′-biphenyl]-3-yl)-3-(2,4-difluorophenyl)-1,2,4-triazine

C21H11F4N3

PROCEDURE

实验过程

5-(3-Bromo-4-fluorophenyl)-3-(2,4-difluorophenyl)-[1,2,4]triazine was coupled to 2-fluorophenylboronic acid by the method of Example 12 to give 5-(2,2′-difluorobiphenyl-5-yl)-3-(2,4-difluorophenyl)-[1,2,4]triazine as a fluffy yellow solid: δH (400 MHz, CDCl3) 6.99-7.10 (2H, m), 7.21-7.23 (1H, m), 7.27-7.31 (1H, m), 7.37-7.48 (3H, m), 8.29-8.35 (3H, m), 9.64 (1H, s); m/z (ES+) 382.