反应详情

(3-Trifluoromethylsulfanylphenyl)oxoacetaldehyde was reacted with 2,4-difluorobenzenecarboximidic hydrazide hydriodide salt (1.13 g, 3.78 mmol) using the method described in Example 1 to give 3-(2,4-difluorophenyl)-5-(3-trifluoromethylsulfanylphenyl)-[1,2,4]triazine as a yellow solid (1.0 g): δH (400 MHz, CDCl3) 7.01-7.13 (2H, m), 7.68 (1H, t, J 7.8 Hz), 7.92 (1H, d, J 7.4 Hz), 8.32-8.39 (2H, m), 8.55 (1H, s), 9.67 (1H, s); m/z (ES+) 370.