反应详情

(3-Trifluoromethylsulfanylphenyl)oxoacetaldehyde was reacted with 4-methoxybenzenecarboximidic hydrazide hydriodide salt (1.11 g, 3.78 mmol) using the method described in Example 1 to give 3-(4-methoxyphenyl)-5-(3-trifluoromethylsulfanylphenyl)-[1,2,4]triazine as a yellow solid (820 g): δH (400 MHz, CDCl3) 3.92 (3H, s), 7.06-7.10 (2H, m), 7.67 (1H, t, J 7.8 Hz), 7.90 (1H, d, J 7.8 Hz), 8.35-8.39 (1H, m), 8.56 (1H, s), 8.60-8.64 (2H, m), 9.55 (1H, s); m/z (ES+) 364.