Hydrazine hydrate (1:1) → HCID 22174882, compound

HRID 1064541Notes

Reaction equation

HRID 1064541 reaction equation
CS[C:3]1[N:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)[N:6]=[CH:5][N:4]=1.O.[NH2:16][NH2:17]>C(O)C>[N:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[C:7]1[N:6]=[CH:5][N:4]=[C:3]([NH:16][NH2:17])[N:8]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22174876HCID 22174876, compound

Product 1

HCID 22174882HCID 22174882, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A stirred solution of the product of step 2 (0.763 g, 3.74 mmol) and hydrazine hydrate (0.22 mL, 3.9 mmol) in ethanol (8 mL) was heated at reflux for 30 minutes. The reaction was cooled in an ice bath and the precipitate was filtered off. Vacuum oven drying afforded crude product as light brown solid. This material was used without further purification in the next step.

Workup

  1. temperatureat reflux for 30 minutes
  2. temperatureThe reaction was cooled in an ice bath
  3. filtrationthe precipitate was filtered off
  4. customVacuum oven drying
  5. customafforded crude product as light brown solid
  6. customThis material was used without further purification in the next step

Sources & evidence

ORD record
ord-60b6830ec36f4834a1b1412712ee3282
Source dataset
uspto-grants-2005_11
Patent number
US06969728B2

Reaction notes

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