HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methanesulfonylbenzene-1-sulfonyl chloride → cis-2-[4-(2-Methanesulphonylbenzenesulphonyl)-3,5-dimethylpiperazin-1-yl]-N-(3 fluoro-2-methylphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735178 | — |
| Reactant | cis-(3,5-Dimethylpiperazin-1-yl)-N-(2-methyl-3-fluorophenyl)acetamide | HCID 69746587 | — |
| Product | cis-2-[4-(2-Methanesulphonylbenzenesulphonyl)-3,5-dimethylpiperazin-1-yl]-N-(3 fluoro-2-methylphenyl)acetamide | HCID 60045643 | — |
Reaction Steps
The title compound was prepared from the product of Example 60 step (i) (0.503 mmol) and 2-methanesulphonylbenzenesulphonyl chloride (0.503 mmol) by the method of Example 58 step (ii) as a white solid. Yield: 17 mg
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969713B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-4fca2684c77a43a6a2b6a24507b0650a |
| Source note | uspto-grants-2005_11 |