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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1064789Generated: November 3, 2026

(S)-2-methylpyrrolidine hydrobromide → 4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-2,3-dihydro-1-benzofuran-5-yl)benzonitrile

https://huagongshe.com/reaction/1064789

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-methylpyrrolidine hydrobromideHCID 20779371—
Reactant2-[5-(4-Cyanophenyl)-2,3-dihydro-1-benzofuran-2-yl]ethyl methanesulfonateHCID 22274466—
Product4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-2,3-dihydro-1-benzofuran-5-yl)benzonitrileHCID 42958579—

Reaction Steps

(2S)-2-Methylpyrrolidine hydrobromide and the product from Example 67D are processed as described in Example 1D to provide the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06969730B2
Source datasetuspto-grants-2005_11
ORD IDord-1e27c59d45f34dbc88fb66a4078ab0a8
Source noteuspto-grants-2005_11