HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-methylpyrrolidine hydrobromide → 4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-2,3-dihydro-1-benzofuran-5-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-methylpyrrolidine hydrobromide | HCID 20779371 | — |
| Reactant | 2-[5-(4-Cyanophenyl)-2,3-dihydro-1-benzofuran-2-yl]ethyl methanesulfonate | HCID 22274466 | — |
| Product | 4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-2,3-dihydro-1-benzofuran-5-yl)benzonitrile | HCID 42958579 | — |
Reaction Steps
(2S)-2-Methylpyrrolidine hydrobromide and the product from Example 67D are processed as described in Example 1D to provide the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06969730B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-1e27c59d45f34dbc88fb66a4078ab0a8 |
| Source note | uspto-grants-2005_11 |