Lithium Hydroxide → HCID 69279891, compound

HRID 1064945Notes

Reaction equation

HRID 1064945 reaction equation
C[O:2][C:3](=[O:31])[C@@H:4]([O:28][CH2:29][CH3:30])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][C:14]2[N:15]=[C:16]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[CH3:26])[O:17][C:18]=2[CH3:19])=[CH:8][C:7]=1[Cl:27].[Li+].[OH-]>>[Cl:27][C:7]1[CH:8]=[C:9]([O:12][CH2:13][C:14]2[N:15]=[C:16]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[CH3:26])[O:17][C:18]=2[CH3:19])[CH:10]=[CH:11][C:6]=1[CH2:5][C@H:4]([O:28][CH2:29][CH3:30])[C:3]([OH:31])=[O:2]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 69280743(S)-3-[2-chloro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-2-ethoxy-propionic acid methyl ester

Product 1

HCID 69279891HCID 69279891, compound

Procedure

In analogy to the procedure described in example 1 g], (S)-3-[2-chloro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-2-ethoxy-propionic acid methyl ester was treated with LiOH to obtain (S)-3-[2-chloro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-2-ethoxy-propionic acid as colorless liquid.

Sources & evidence

ORD record
ord-4b26f45ad26942159c97b28dcde456a7
Source dataset
uspto-grants-2005_11
Patent number
US06969725B2

Reaction notes

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