Toluene → [2-Isopropoxyethyl]benzene

HRID 1065058Notes

Reaction equation

HRID 1065058 reaction equation
C1(C)C=CC=CC=1.C(OC(=O)CC)(=O)CC.C(OC(=O)CC)(=O)CC.C1(C)C=CC=CC=1.C1(CCO)C=CC=CC=1.[CH:42]([O:45][CH2:46][CH2:47][C:48]1[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=1)([CH3:44])[CH3:43]>O>[CH:42]([O:45][CH2:46][CH2:47][C:48]1[CH:49]=[CH:50][CH:51]=[CH:52][CH:53]=1)([CH3:44])[CH3:43]

Participants

5

Reactant 3

HCID 1140TolueneHCID 31263Propionic anhydrideHCID 86738357HCID 86738357, compound

Product 1

HCID 106442[2-Isopropoxyethyl]benzene

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To the toluene mixture is added 260 grams of propionic anhydride and the propionic anhydride/toluene/phenylethyl alcohol/isopropyl phenethylether mixture is then refluxed for a period of 30 minutes. The reaction mass is then cooled down and one liter of water is added thereto. The reaction mass is then washed with 50% caustic followed by saturated sodium chloride and then neutralized with saturated sodium bicarbonate.

Workup

  1. temperatureThe reaction mass is then cooled down
  2. washThe reaction mass is then washed with 50%

Sources & evidence

ORD record
ord-c202b076e4da4d23ac53595b4b225995
Source dataset
uspto-grants-1982_05
Patent number
US04328206

Reaction notes

Loading…