Potassium Fluoride → HCID 12850199, compound

HRID 1065067Notes

Reaction equation

HRID 1065067 reaction equation
[Cl:1][C:2]1[C:11]([Cl:12])=[N:10][C:9]2[C:4](=[CH:5][C:6]([Cl:17])=[C:7]([S:13](Cl)(=[O:15])=[O:14])[CH:8]=2)[N:3]=1.[F-:18].[K+]>C(Cl)Cl.[Br-].C([N+](CC)(CC)CC)C1C=CC=CC=1.O>[Cl:1][C:2]1[C:11]([Cl:12])=[N:10][C:9]2[C:4](=[CH:5][C:6]([Cl:17])=[C:7]([S:13]([F:18])(=[O:15])=[O:14])[CH:8]=2)[N:3]=1

Participants

6

Reactant 2

HCID 522689Potassium FluorideHCID 12906275HCID 12906275, compound

Product 1

HCID 12850199HCID 12850199, compoundYield 80.1%

Reagents, catalysts & solvents 3

HCID 165294Benzyltriethylammonium bromideCatalystHCID 962WaterSolventHCID 6344DichloromethaneSolvent

Procedure

To a solution of 46 g of 2,3,7-trichloro-6-quinoxalinesulfonyl chloride in 200 ml of methylene chloride were added 0.42 g of benzyltriethylammonium bromide and a solution of 20.2 g of potassium fluoride in 20.9 ml of water. The resulting mixture was stirred for 17.5 hours at ambient temperature, filtered, dried over magnesium sulfate, treated with activated carbon and filtered again. Solvent was removed under vacuum, leaving a yellowish solid which was recrystallized from hexane to provide 35 g of 2,3,7-trichloro-6-quinoxalinesulfonyl fluoride as a light-yellow solid, having a melting point of 111°-113°.

Workup

  1. filtrationfiltered
  2. dry with materialdried over magnesium sulfate
  3. additiontreated with activated carbon
  4. filtrationfiltered again
  5. customSolvent was removed under vacuum
  6. customleaving a yellowish solid which
  7. customwas recrystallized from hexane

Sources & evidence

ORD record
ord-83f20045f6934966b6a3c2cf6bebc669
Source dataset
uspto-grants-1982_05
Patent number
US04328228

Reaction notes

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