HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 12850587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-(2-Tosyloxyethyl)-1,4-benzodioxan | HCID 12850582 | — |
| Reactant | 1-(Piperidin-4-yl)imidazolidin-2-one | HCID 13031757 | — |
| Solvent | Methyl Isobutyl Ketone | HCID 7909 | — |
| Product | HCID 12850587 | HCID 12850587 | — |
Reaction Steps
The mixture of 4.9 g of 2-(2-tosyloxyethyl)-1,4-benzodioxan, 2.54 g of 1-(4-piperidyl)-2-imidazolidinone, 5 g of anhydrous sodium carbonate and 100 ml of 4-methyl-2-pentanone is stirred and refluxed for 3 days. It is filtered, evaporated and the residue recrystallized from isopropanol, to yield the 1-[1-[2-(1,4-benzodioxan-2-yl)-ethyl]-4-piperidyl]-2-imidazolidinone of the formula ##STR9## melting at 125°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04329348 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-9d7c9c7972d349fbaefdb7ce77710c72 |
| Source note | uspto-grants-1982_05 |