HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 20540237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one | HCID 70556 | — |
| Reactant | 4-Oxo-1-phenylcyclohexanenitrile | HCID 91282 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20540237 | HCID 20540237 | — |
Reaction Steps
A mixture of 5 parts of 4-oxo-1-phenyl-1-cyclohexanecarbonitrile, 5.8 parts of 1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one, 0.1 parts of 4-methylbenzenesulfonic acid and 225 parts of methylbenzene is stirred and refluxed overnight with water-separator. The reaction mixture is cooled and evaporated, yielding 10.35 parts of 4-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)-1-phenyl-3-cyclohexene-1-carbonitrile as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04329353 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-7ab6cbbe6b1445fe8303faaecf61c59c |
| Source note | uspto-grants-1982_05 |