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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1065356Generated: October 30, 2026

8-Hydroxy-3,4-dihydroquinolin-2(1h)-one → 8-(4-Phenylmercapto-butoxy)-3,4-dihydro-carbostyril

https://huagongshe.com/reaction/1065356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Hydroxy-3,4-dihydroquinolin-2(1h)-oneHCID 268239—
Reactant4-Phenylmercapto-butylbromideHCID 11184148—
Product8-(4-Phenylmercapto-butoxy)-3,4-dihydro-carbostyrilHCID 53918146—

Reaction Steps

Prepared analogous to Example 4 from 8-hydroxy-3,4-dihydro-carbostyril (see J. D. Loudon et al., J. Chem. Soc. 1955, 743-744) and 4-phenylmercapto-butyl bromide (bp. 96°-103° C. at 0.02 mm Hg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04329347
Source datasetuspto-grants-1982_05
ORD IDord-33890bda7f1745d5bd6ceee1710694e2
Source noteuspto-grants-1982_05