HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(4-Phenylsulfonyl-butoxy)-carbostyril → 6-(4-Phenylsulfonyl-butoxy)-3,4-dihydro-carbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(4-Phenylsulfonyl-butoxy)-carbostyril | HCID 20540040 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-(4-Phenylsulfonyl-butoxy)-3,4-dihydro-carbostyril | HCID 20540049 | — |
Reaction Steps
107 mgm of 6-(4-phenylsulfonyl-butoxy)-carbostyril were suspended in 15 ml of methanol, the suspension was admixed with 40 mgm of palladium-on-charcoal, and the mixture was hydrogenated at 50° C. and a hydrogen pressure of 2.5 bar for 14 hours. After filtering off the catalyst and evaporating the clear solution, a colorless crystalline residue was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04329347 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-48360c24842a4da0ac8a27e0a38591ed |
| Source note | uspto-grants-1982_05 |