Hydrogen Peroxide → HCID 20539970, compound

HRID 1065393Notes

Reaction equation

HRID 1065393 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9][CH2:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=[O:25])[CH2:19][CH2:18]2.[OH:26]O>C(O)(=O)C>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[S:9]([CH2:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:16]=[C:17]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=[O:25])[CH2:19][CH2:18]2)=[O:26]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 20539997HCID 20539997, compound

Product 1

HCID 20539970HCID 20539970, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

A suspension of 5.55 gm (0.014 mol) of 6-[4-(2,5-dichlorophenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril in 40 ml of glacial acetic acid was admixed with 1.19 ml of an aqueous 40.06% solution of hydrogen peroxide (0.014 mol) dissolved in 1.5 ml of glacial acetic acid, and the mixture was stirred at room temperature. The suspension cleared, and an almost clear solution was obtained. After 70 hours white crystals separated out, which were suction-filtered off and recrystallized from ethanol.

Workup

  1. customan almost clear solution was obtained
  2. customAfter 70 hours white crystals separated out
  3. filtrationwhich were suction-filtered off
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-d08cfd311aa24755a14a68497295ebab
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

Loading…