Hydrogen Peroxide → HCID 20540099, compound

HRID 1065397Notes

Reaction equation

HRID 1065397 reaction equation
BrCCCC[O:6]C1C=C2C(=CC=1)NC(=O)CC2.SC1C=CN=CC=1.[N:25]1[CH:30]=[CH:29][C:28]([S:31][CH2:32][CH2:33][CH2:34][CH2:35][O:36][C:37]2[CH:38]=[C:39]3[C:44](=[CH:45][CH:46]=2)[NH:43][C:42](=[O:47])[CH2:41][CH2:40]3)=[CH:27][CH:26]=1.OO>>[N:25]1[CH:30]=[CH:29][C:28]([S:31]([CH2:32][CH2:33][CH2:34][CH2:35][O:36][C:37]2[CH:38]=[C:39]3[C:44](=[CH:45][CH:46]=2)[NH:43][C:42](=[O:47])[CH2:41][CH2:40]3)=[O:6])=[CH:27][CH:26]=1

Participants

5

Reactant 4

HCID 784Hydrogen PeroxideHCID 131098086-(4-Bromobutoxy)-3,4-dihydro-carbostyrilHCID 20540127HCID 20540127, compoundHCID 178418431pyridine-4-thiol

Product 1

HCID 20540099HCID 20540099, compound

Procedure

Prepared analogous to Example 122 from 6-(4-bromo-butoxy)-3,4-dihydro-carbostyril and 4-mercapto-pyridine and subsequent oxidation of the intermediate 6-[4-(4-pyridyl-mercapto)-butoxy]-3,4-dihydro-carbostyril (m.p. 128°-133° C.) with hydrogen peroxide analogous to Example 123.

Sources & evidence

ORD record
ord-d3be88a7d1f64ca9892fa470d263cb61
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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