HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → HCID 54278658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | alpha,alpha'-Dichloro-p-xylene | HCID 12171 | — |
| Reactant | 6-Hydroxy-3,4-dihydro-2(1H)-quinolinone | HCID 2774040 | — |
| Reactant | HCID 20539969 | HCID 20539969 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 54278658 | HCID 54278658 | — |
Reaction Steps
p-Xylylene dichloride was reacted with thiophenol in a mol ratio of 1:1 in the presence of excess potassium carbonate in dimethylsulfoxide. The obtained 4-(phenyl-mercapto-methyl)-benzyl chloride (identification: thin-layer chromatogram) was further reacted with 6-hydroxy-3, 4-dihydro-carbostyril analogous to Example 140 without isolation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04329347 |
| Source dataset | uspto-grants-1982_05 |
| ORD ID | ord-3da45e9a5a6e4bbeb1c506f795f13a14 |
| Source note | uspto-grants-1982_05 |