Hydrochloric Acid → HCID 12616415, compound

HRID 1065545Notes

Reaction equation

HRID 1065545 reaction equation
O.O.O.O.C([NH:8][C:9]12[CH2:22][C:13]3([NH:23]C(=O)C)[CH2:14][C:15]([NH:18]C(=O)C)([CH2:17][C:11]([NH:27]C(=O)C)([CH2:12]3)[CH2:10]1)[CH2:16]2)(=O)C.[ClH:31]>>[ClH:31].[ClH:31].[ClH:31].[ClH:31].[NH2:8][C:9]12[CH2:16][C:15]3([NH2:18])[CH2:17][C:11]([NH2:27])([CH2:12][C:13]([NH2:23])([CH2:14]3)[CH2:22]1)[CH2:10]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20540997HCID 20540997, compound

Product 1

HCID 12616415HCID 12616415, compoundYield 82%

Procedure

1,3,5,7-Tetraacetamidoadamantane tetrahydrate (2.0 g=4.6 mmoles) was dissolved in 18% hydrochloric acid (30 ml of concentrated hydrochloric acid diluted with 30 ml of water) and the solution was refluxed for three hours. The crystalline product thus obtained was separated from the mixture by filtration, washed with acetone and dried. 1.29 g of product, mp 360° C. (lit.>360° C., H. Stetter and C. Wulff, Chem. Ber. 93, 1366 (1960)), corresponding to an 82.0% yield, were obtained.

Workup

  1. temperaturethe solution was refluxed for three hours
  2. customThe crystalline product thus obtained
  3. customwas separated from the mixture by filtration
  4. washwashed with acetone
  5. customdried

Sources & evidence

ORD record
ord-03e985e9f3b84661bdc30921bb4c9324
Source dataset
uspto-grants-1982_05
Patent number
US04329522

Reaction notes

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