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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1065636Generated: October 30, 2026

2-Chloroquinoline → N-Methyl-3-phenyl-3-(2-quinolyloxy)propylamine

https://huagongshe.com/reaction/1065636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroquinolineHCID 11928—
ReactantSodium hydrideHCID 24758—
Reactant3-Methylamino-1-phenylpropanolHCID 2733989—
SolventDimethyl SulfoxideHCID 679—
ProductN-Methyl-3-phenyl-3-(2-quinolyloxy)propylamineHCID 20539674—

Reaction Steps

Following the method of Example 4, reaction of 3-hydroxy-N-methyl-3-phenylpropylamine, sodium hydride and 2-chloroquinoline in DMSO gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04330546
Source datasetuspto-grants-1982_05
ORD IDord-67e5b6efb350441ca2329c3af8282cad
Source noteuspto-grants-1982_05