Sodium hydride → HCID 20539672, compound

HRID 1065637Notes

Reaction equation

HRID 1065637 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([OH:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:3].[H-].[Na+].Br[C:17]1[S:18][CH:19]=[CH:20][N:21]=1>CS(C)=O>[CH3:1][N:2]([CH2:4][CH2:5][CH:6]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[O:13][C:17]1[S:18][CH:19]=[CH:20][N:21]=1)[CH3:3]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 764302-BromothiazoleHCID 1106653-(Dimethylamino)-1-phenylpropan-1-ol

Product 1

HCID 20539672HCID 20539672, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Following the method of Example 3, reaction of N,N-dimethyl-3-hydroxy-3-phenylpropylamine, sodium hydride and 2-bromothiazole in DMSO gives the title compound.

Sources & evidence

ORD record
ord-9dc61226013e494182c0e9d09b3e9f82
Source dataset
uspto-grants-1982_05
Patent number
US04330546

Reaction notes

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