Hydrochloric Acid → HCID 12962019, compound

HRID 1065709Notes

Reaction equation

HRID 1065709 reaction equation
[CH3:1][C:2]1[C:19]2[C@@H:18]3[C@H:9]([C@H:10]4[C@@:14]([CH2:16][CH2:17]3)([CH3:15])[C@@H:13]([NH:20][CH3:21])[C@H:12]([OH:22])[CH2:11]4)[CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]([OH:23])[CH:3]=1.[ClH:24]>CO>[ClH:24].[CH3:1][C:2]1[C:19]2[C@@H:18]3[C@H:9]([C@H:10]4[C@@:14]([CH2:16][CH2:17]3)([CH3:15])[C@@H:13]([NH:20][CH3:21])[C@H:12]([OH:22])[CH2:11]4)[CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]([OH:23])[CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12962018HCID 12962018, compound

Product 1

HCID 12962019HCID 12962019, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a similar way as described infra Example XXIII (b) the compound of Example XXXIII (a) was converted into its hydrochloride, m.p. 280°-291° C. (decomp.), [α]D +115.4° (c 1.13 in methanol).

Sources & evidence

ORD record
ord-0e3e27bb4324417ea0ba9032eced9a1f
Source dataset
uspto-grants-1982_05
Patent number
US04330539

Reaction notes

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