Water → HCID 12850209, compound

HRID 1065731Notes

Reaction equation

HRID 1065731 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]2[O:13][CH2:12][C:11]([CH2:16][CH3:17])([CH2:14][CH3:15])[CH2:10][O:9]2)[CH:5]=[CH:6][CH:7]=1.[CH3:18][N:19]=[C:20]=[O:21].O>CC(C)=O>[CH3:18][NH:19][C:20](=[O:21])[NH:1][C:2]1[CH:3]=[C:4]([CH:8]2[O:9][CH2:10][C:11]([CH2:16][CH3:17])([CH2:14][CH3:15])[CH2:12][O:13]2)[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 962WaterHCID 12228Methyl IsocyanateHCID 12850208HCID 12850208, compound

Product 1

HCID 12850209HCID 12850209, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Nine and four tenths grams (9.4 g) of 2-(m-aminophenyl)-5,5-diethyl-1,3-dioxane was reacted with 3 g of methyl isocyanate in 75 ml of acetone. The mixture was refluxed for between one and two hours and poured into water and the product collected by filtration. The yield was 11.7 g of the title compound, m.p. 112°-125° C. Trituration with diethyl ether raised the melting point to 135°-137° C.

Workup

  1. temperatureThe mixture was refluxed for between one and two hours
  2. filtrationthe product collected by filtration
  3. temperatureTrituration with diethyl ether raised the melting point to 135°-137° C.

Sources & evidence

ORD record
ord-8e00248cca1648faa23d749819a885ab
Source dataset
uspto-grants-1982_05
Patent number
US04331466

Reaction notes

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