Hydrazine hydrate (1:1) → HCID 20538683, compound

Participants

Reaction Steps

To a stirred solution of 4,4-dimethyl-1,1-bis(methylthio)-1-penten-3-one (18.4 g) in ethanol, was added dropwise with stirring hydrazine hydrate (5.3 g), keeping the temperature below 25°. The reaction mixture was stirred briefly at room temperature, then refluxed for 2 hours. Evaporation of the solvent, and trituration with ether, afforded 3-t-butylpyrazole-5-thione (7.8 g, 20% yield), of melting point 147°-8°.

Provenance & Evidence