反应详情

温度

-10 °C

Boron trifluoride diethyl etherate (138.7 g, 0.98 mole) is added to a diethyl ether solution of pentafluorophenylmagnesium bromide (3326 g, 4.17 moles) formed as in Example 24. The addition is at a rate allowing the mixture to reach reflux temperature. The mixture is heated at reflux for 18 hours. This mixture is then cooled to −10° C. and N,N-dimethylanilinium chloride (1142 grams, 2.06 moles) previously formed from concentrated HCl, water, and N,N-dimethylaniline is slowly added while keeping the temperature at about 0° C. After the addition, the mixture is stirred for one hour at −5° C. to 0° C. Then the two phases are separated, and the organic phase is washed with water and dried over MgSO4. The N,N-dimethylanilinium tetrakis(pentafluorophenyl)borane is precipitated by addition of hexane with stirring, and recovered by filtration.

1. customformed as in Example 24
2. additionThe addition
3. temperatureto reach reflux temperature
4. temperatureThe mixture is heated
5. temperatureat reflux for 18 hours