1-Methylpiperazine → HCID 135455994, compound

Participants

Reaction Steps

Compound 6a (1.25 g, 0.003 mole) was dissolved in THF (10 ml) and added to a solution of 1-methylpiperazine (1 ml) in THF (10 ml). The resulting mixture was stirred at room temperature for 1 h. The THF was then removed in vacuo, and the residue was treated with cold water (50 ml). The resulting white precipitate was filtered under suction, washed with water (2×10 ml), drained and recrystallized from 90% ethanol, thereby yielding 7a.

Provenance & Evidence