HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Quinolin-3-yl)piperidin-4-ol → 1-(3-(2-Tert-butylphenoxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Quinolin-3-yl)piperidin-4-ol | HCID 21198010 | — |
| Reactant | 3-Chloropropyl 2-tert-butylphenyl ether | HCID 21198113 | — |
| Product | 1-(3-(2-Tert-butylphenoxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine | HCID 9802150 | 39% |
Reaction Steps
Beginning with 0.298 gm (1.3 mMol) 3-chloropropyl 2-tert-butylphenyl ether and 0.300 gm (1.3 mMol) 4-hydroxy-4-(quinolin-3-yl)piperidine, 0.212 gm (39%) of the title compound were recovered as a white, waxy solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242450B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-6f8e1e14e946475bbcc8fdb505dda2c3 |
| Source note | uspto-grants-2001_06 |