Potassium Carbonate → HCID 21197764, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-amino-4-methanesulfonylbenzenesulfonamide (2.5 g), potassium carbonate (1.66 g) and isopropyl isothiocyanate (1.22 g) in 20 ml of dry acetone was heated at 50° C. for 18 h. Then the reaction mixture was evaporated in vacuo and the residue was dissolved in 25 ml of water. Then the solution was adjusted to pH 2 by dropwise addition of 4 M HCl at 0° C. with stirring. After stirring for 2 h the product was filtered off and dried, yielding the title compound as white crystals; m.p. 151-153° C.

Provenance & Evidence