反应详情

Starting from 2-amino-4-methylbenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-3-chlorobenzenesulfonyl)-N′-isopropylthiourea was prepared; m.p. 124-125° C. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 204-206° C.

1. customwas prepared