HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 178456962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Isopropyl Isothiocyanate | HCID 75263 | — |
| Reactant | 2-Amino-4-methylbenzenesulfonamide | HCID 11436538 | — |
| Reactant | N-(2-amino-3-chlorobenzenesulfonyl)-N'-isopropylthiourea | HCID 21197874 | — |
| Product | HCID 178456962 | HCID 178456962 | — |
Reaction Steps
Starting from 2-amino-4-methylbenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-3-chlorobenzenesulfonyl)-N′-isopropylthiourea was prepared; m.p. 124-125° C. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 204-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242443B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-03d968f72dbe4be291853f648f68b544 |
| Source note | uspto-grants-2001_06 |