反应详情

Starting from 2-amino-4-methylbenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-4-methylbenzenesulfonyl)-N′-isopropylthiourea was prepared, m.p. 137-139° C. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 309-311° C.

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