HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 178422564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Isopropyl Isothiocyanate | HCID 75263 | — |
| Reactant | 2-Amino-4-methylbenzenesulfonamide | HCID 11436538 | — |
| Reactant | N-(2-amino-4-methylbenzenesulfonyl)-N'-isopropylthiourea | HCID 21197735 | — |
| Product | HCID 178422564 | HCID 178422564 | — |
Reaction Steps
Starting from 2-amino-4-methylbenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-4-methylbenzenesulfonyl)-N′-isopropylthiourea was prepared, m.p. 137-139° C. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 309-311° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242443B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-82cd63e0e3be427a8df034328d6160d7 |
| Source note | uspto-grants-2001_06 |