Isopropyl Isothiocyanate → HCID 178456977, compound

Participants

Reaction Steps

Starting from 2-amino-4-phenoxybenzenesulfonamide and isopropyl isothiocyanate, and following a procedure analogous to the one described in Example 4a, N-(2-amino-4-phenoxybenzenesulfonyl)-N′-isopropylthiourea was prepared. The impure crude product was used without purification. Subsequent ring closure with phosgene by a procedure analogous to the one described in Example 4b gave the title compound; m.p. 250-252° C.

Provenance & Evidence