Benzenesulfonamide, 2-amino-4,5-dichloro- → HCID 178446292, compound

HRID 1066112Notes

Reaction equation

HRID 1066112 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([Cl:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[CH3:14][CH:15]([N:19]=[C:20]=S)[CH:16]([CH3:18])[CH3:17]>C(OCC)(=O)C>[Cl:8][C:6]1[C:5]([Cl:9])=[CH:4][C:3]2[S:10](=[O:12])(=[O:11])[N:13]=[C:20]([NH:19][CH:15]([CH3:14])[CH:16]([CH3:18])[CH3:17])[NH:1][C:2]=2[CH:7]=1

Participants

4

Reactant 2

HCID 204803Benzenesulfonamide, 2-amino-4,5-dichloro-HCID 5383422-Isothiocyanato-3-methylbutane

Product 1

HCID 178446292HCID 178446292, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared from 2-amino-4,5-dichlorobenzenesulfonamide and 1,2-dimethylpropyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 242-250° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 0.90 (d, 3H, CH3), 0.91 (d, 3H, CH3), 1.10 (d, 1H, CH3), 1.77 (m, 1H, CH(CH3)2), 3.71 (m, 1H, NHCH), 7.29 (br., 1H, NH), 7.49 (br.s, 1H, ArH), 7.89 (s, 1H, ArH), 10.41 (br.s, 1H, NH); MS: m/e 335/337/339 (M+); (C12H15N3Cl2O2S1) calc. C, 42.87; H, 4.50; N, 12.50; found C, 42.94; H, 4.68; N, 12.45.

Sources & evidence

ORD record
ord-eaa78a3585ad4195b5d250b320c5727b
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

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