2-Butanamine, 3,3-dimethyl- → HCID 178463650, compound

Participants

Reaction Steps

Starting from 7-bromo-3-chloro-4H-1,2,4-benzothiadiazine 1,1-dioxide (300 mg; 1.01 mmol) and 1,2,2-trimethylpropylamine (359 mg; 4.04 mmol) with the use of same procedure as in example 21 200 mg (54.9%) of the title compound was prepared; m.p. >220° C.; 1H-NMR (DMSO-d6) ppm; 10.35 (s, 1H, NH), 7.78 (d, 1H, H-8), 7.6 (dd, 1H, H-6), 7.12 (br d, 1H, H-5), 6.95 (br, 1H, NH), 3.72 (q, 1H, CH), 1.10 (d, 3H, CH3), 0.92 (s, 9H, 3×CH3); MS:EI/70eV: 361 (M+1), 304, 277, 236, 170, 116, 90, 44.

Provenance & Evidence