Benzenesulfonamide, 2-amino-4,5-dichloro- → HCID 178446293, compound

HRID 1066115Notes

Reaction equation

HRID 1066115 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([Cl:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[CH3:14][CH:15]([N:19]=[C:20]=S)[CH2:16][CH2:17][CH3:18]>C(OCC)(=O)C>[Cl:8][C:6]1[C:5]([Cl:9])=[CH:4][C:3]2[S:10](=[O:12])(=[O:11])[N:13]=[C:20]([NH:19][CH:15]([CH3:14])[CH2:16][CH2:17][CH3:18])[NH:1][C:2]=2[CH:7]=1

Participants

4

Reactant 2

HCID 204803Benzenesulfonamide, 2-amino-4,5-dichloro-HCID 5365792-Isothiocyanatopentane

Product 1

HCID 178446293HCID 178446293, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared from 2-amino-4,5-dichlorobenzenesulfonamide and 2-pentyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 217-220° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 0.90 (t, 3H, CH3), 1.14 (d, 3H, CH3), 1.20-1.55 (m, 4H, CH2CH2), 3.83 (m, 1H, NHCH), 7.33 (br., 1H, NH), 7.49 (br.s, 1H, ArH), 7.89 (s, 1H, ArH), 10.48 (br.s, 1H, NH); MS: m/e 335/337/339 (M+).

Sources & evidence

ORD record
ord-de7c929b624b45c29f495980cc3596f3
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

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