Isopropyl Isothiocyanate → HCID 178456983, compound

HRID 1066133Notes

Reaction equation

HRID 1066133 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([I:8])=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH:13]([N:16]=[C:17]=S)([CH3:15])[CH3:14]>>[I:8][C:5]1[CH:6]=[CH:7][C:2]2[NH:1][C:17]([NH:16][CH:13]([CH3:15])[CH3:14])=[N:12][S:9](=[O:11])(=[O:10])[C:3]=2[CH:4]=1

Participants

3

Reactant 2

HCID 75263Isopropyl IsothiocyanateHCID 223240882-Amino-5-iodobenzenesulfonamide

Product 1

HCID 178456983HCID 178456983, compound

Procedure

The title compound was prepared from 2-amino-5-iodobenzenesulfonamide and isopropyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 305-307° C. dec; 1H-NMR (DMSO-d6): δ 1.17 (d, 6H, CH(CH3)2), 3.91 (m, 1H, CH(CH3)2), 7.02 (d, 1H, ArH), 7.15 (br., 1H, NH), 7.8-7.9 (m, 2H, ArH), 10.43 (br.s, 1H, NH); MS: m/e 365 (M+, 27%); (C10H12N3I1O2S1) calc. C, 32.89; H, 3.31; N, 11.51, found C, 32.79; H, 3.41; N, 11.27.

Sources & evidence

ORD record
ord-1a82c151f55540cd8a074a0ada525b73
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

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