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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1066309Generated: November 1, 2026

Nipecotic Acid → 1-Acetyl-3-piperidinecarboxylic acid

https://huagongshe.com/reaction/1066309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNipecotic AcidHCID 4498—
ReactantAcetic AnhydrideHCID 7918—
Product1-Acetyl-3-piperidinecarboxylic acidHCID 1404389697.4%

Reaction Steps

Nipecotic acid (3.87 grams) (30.0 mmoles) was reacted with acetic anhydride (9.17 grams) (90 mmoles) as described in Preparative Example 13A to give the title compound (Yield: 5.0 grams, 97%, MH+ 172).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06242458B1
Source datasetuspto-grants-2001_06
ORD IDord-e404460836eb4adea77f6dca7aa0cac2
Source noteuspto-grants-2001_06