HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guanine → Formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guanine | HCID 135398634 | — |
| Reactant | N-(2,6-diamino-4-oxo-1H-pyrimidin-5-yl)formamide | HCID 178508810 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | Formamide | HCID 713 | — |
| Product | N-(2,6-diamino-4-oxo-1H-pyrimidin-5-yl)formamide | HCID 178508810 | — |
Reaction Steps
The objects of the invention, and others, may be accomplished with a process for the preparation of guanine starting from 2,4-diamino-5-formylamino-6-hydroxypyrimidine (DAFHP), which comprises reacting isolated DAFHP in the absence of formamide in formic acid, with or without addition of water under reflux conditions, to produce guanine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242599B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-a0cbe2276ea3440cbde73905acc9b8eb |
| Source note | uspto-grants-2001_06 |