HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 15838445, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Iodine | HCID 807 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile | HCID 132981 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15838445 | HCID 15838445 | — |
Reaction Steps
787 mg of triphenyl phosphine, 204 mg of imidazole, 762 mg of iodine and 5 ml of methylene chloride are introduced, the suspension is agitated for 45 minutes at ambient temperature, then over about 3 minutes, 1.1 g of 4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)-2-(trifluoromethyl)-benzonitrile obtained in Example 1 of EP 0,580,459 in 7 ml of methylene chloride is added. Rinsing is carried out with 1 ml of methylene chloride followed by agitation for 4 hours at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242611B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-6e48c9b7cb8c4d90a0bc6e68af2c237a |
| Source note | uspto-grants-2001_06 |